Jones Oxidation

August 7, 2024·Devraj Bagchi
Devraj Bagchi
Oxidation Carboxylic Acid Ketone Harsh

Jones Oxidation is a harsh oxidation method used to convert 1° Alcohols (Primary) to Carboxylic Acids and 2° Alcohols (Secondary) to Ketones. Additionally, aldehydes are converted to carboxylic acids as well.

Oxidation Uses

General Scheme of Dess Martin Oxidation

Primary Alcohol to Carboxylic Acid Scheme

Chromium(VI) oxide and Sulfuric acid is used alongside acetone as a solvent to convert the primary alcohol into an aldehyde intermediate. This aldehyde intermediate undergoes reaction with the same oxidizing agent [O] to form a carboxylic acid.

General Scheme of Jones Oxidation for Secondary Alcohols

Jones Oxidation can convert secondary alcohols to ketones.

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Database Info

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