Jones Oxidation
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Jones Oxidation is a harsh oxidation method used to convert 1° Alcohols (Primary) to Carboxylic Acids and 2° Alcohols (Secondary) to Ketones. Additionally, aldehydes are converted to carboxylic acids as well.
Oxidation Uses
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General Scheme of Dess Martin Oxidation
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Primary Alcohol to Carboxylic Acid Scheme
Chromium(VI) oxide and Sulfuric acid is used alongside acetone as a solvent to convert the primary alcohol into an aldehyde intermediate. This aldehyde intermediate undergoes reaction with the same oxidizing agent [O] to form a carboxylic acid.
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General Scheme of Jones Oxidation for Secondary Alcohols
Jones Oxidation can convert secondary alcohols to ketones.
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Database Info
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